COVID-19 Vaccination

May 15, 2022

What You Need to Know About COVID-19 Vaccination and Fertility

  • COVID-19 vaccination is recommended for people who are trying to get pregnant now or might become pregnant in the future, as well as their partners.
  • People who are trying to get pregnant now or might become pregnant in the future should stay up to date with their COVID-19 vaccines, including getting a COVID-19 booster shot when it’s time to get one.
  • There is currently no evidence that any vaccines, including COVID-19 vaccines, cause fertility problems (problems trying to get pregnant) in women or men.
  • COVID-19 can make you very sick during pregnancy. Additionally, if you have COVID-19 during pregnancy, you are at increased risk of complications that can affect your pregnancy and developing baby.

CDC and Medical Professionals Recommend COVID-19 Vaccination for People Who Want to Have Children

COVID-19 vaccination is recommended for people who are trying to get pregnant now or might become pregnant in the future, as well as their partners.

Professional medical organizationsexternal icon serving people of reproductive age, including adolescents, emphasize that there is no evidence that COVID-19 vaccination causes problems with fertility.1–5 These organizations also recommend COVID-19 vaccination for people who may consider getting pregnant in the future.

Pregnancy After Vaccination

Many people have become pregnant after receiving a COVID-19 vaccine, including some who got vaccinated during COVID-19 vaccine clinical trials.6-8 In addition, a recent reportexternal icon using the v-safe COVID-19 vaccine pregnancy safety monitoring system data showed that 4,800 people had a positive pregnancy test after receiving the first dose of an mRNA COVID-19 vaccine. Another reportexternal icon using data from eight U.S. healthcare systems documented more than 1,000 people who completed COVID-19 vaccination (with any COVID-19 vaccine) before becoming pregnant.

Evidence continues to grow showing that COVID-19 vaccination is safe and effective during pregnancy.
Learn more: COVID-19 Vaccines While Pregnant or Breastfeeding.

No Evidence that COVID-19 Vaccines Affect Fertility

There is currently no evidence that vaccine ingredients or antibodies made following COVID-19 vaccination would cause any problems with becoming pregnant now or in the future. 

  • Recent studies have found no differences in pregnancy success rates among women who had antibodies from COVID-19 vaccines or from a recent COVID-19 infection, and women who had no antibodies, including for patients undergoing assisted reproductive technology procedures (e.g., in vitro fertilization).11-13
  • A studyexternal icon of more than 2,000 females aged 21-45 years and their partners found that COVID-19 vaccination of either partner did not affect the likelihood of becoming pregnant.14

Like with all vaccines, scientists are studying COVID-19 vaccines carefully and will continue to report findings as they become available.

Learn how COVID-19 vaccines work.

Limited, Temporary Impact of COVID-19 Vaccines on Menstrual Cycles

Results from recent research studiesexternal icon 15,16 show that people who menstruate may observe small, temporary changes in menstruation after COVID-19 vaccination, including:

  • Longer-lasting menstrual periods
  • Shorter intervals between periods
  • Heavier bleeding than usual

Despite these temporary changes in menstruation, there is no evidence that COVID-19 vaccines cause fertility problems.

Research Studies of Fertility in Healthy Men

Safety Monitoring

COVID-19 vaccines are undergoing the most intense safety monitoring in U.S. history. Data continue to accumulate and show that COVID-19 vaccines are safe and effective for use before and during pregnancy.

Learn more about getting a COVID-19 vaccine while pregnant or breastfeeding.

Managing Side Effects

If you have side effects after COVID-19 vaccination, talk to your healthcare provider about taking over-the-counter medicine, such as ibuprofen, acetaminophen, or antihistamines, for any pain or discomfort you may experience, including fever. You can take these medications to relieve short-term side effects after getting vaccinated if you have no medical reasons that prevent you from taking these medications.

Fever, for any reason, has been associated with adverse pregnancy outcomes. Fever in pregnancy may be treated with acetaminophen as needed, in moderation, and in consultation with a healthcare provider. It is Recommendations

CDC recommends that people who are trying to get pregnant now or might become pregnant in the future, as well as their partners, get vaccinated and stay up to date on their COVID-19 vaccines, including getting a COVID-19 booster shot when it’s time to get one. Pfizer-BioNTech or Moderna (mRNA COVID-19 vaccines) are preferred over the Johnson & Johnson’s Janssen COVID-19 vaccine. However, the J&J/Janssen COVID-19 vaccine may be considered in some situations.