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WASHINGTON — The Biden administration said Tuesday it plans to develop a proposed rule requiring tobacco companies to reduce nicotine levels in cigarettes sold in the United States to minimally or nonaddictive levels, an effort that, if successful, could have an unprecedented effect in slashing smoking-related deaths and threaten a politically powerful industry.

The initiative was included in the administration’s “unified agenda,” a compilation of planned federal regulatory actions released twice a year. The spring agenda was released Tuesday.

The administration said the FDA intends to develop a proposed tobacco product standard “that would establish a maximum nicotine level in cigarettes and certain finished tobacco products.”

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Such a step, the administration said, would reduce addictiveness to certain tobacco products and give addicted users a greater ability to quit, and it would help prevent young people from becoming regular smokers.

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