A chemical leak from a railroad tanker-train car led officials in Southern California on Friday to temporarily shut down a major freeway and evacuate more than 100 homes amid fears of an explosion.

Late Friday night, officials determined the contents of the railcar “are not an imminent threat” to the 215 freeway and reopened the highway, according to a Twitter statement from Cal Fire and the Riverside County Fire Department.

Evacuation warnings and orders were lifted for most of the area, except for the area west of the highway, where an evacuation order remains in place, the statement said.

Officials previously said the train car was leaking a chemical called styrene, which is used to make plastic products. Styrene is a highly flammable substance that can cause skin and eye irritation and is toxic if inhaled, according to the National Institutes of Health. One of the main concerns was that the car would explode as pressure built up inside the car and temperatures rose during the day. 

The train car was stopped on a railway that runs parallel to the 215 freeway, near commercial businesses and a residential neighborhood just north of Perris, California, 75 miles inland from Los Angeles. Styrene is typically kept at about 85 degrees, but temperatures in the container had reached at least 323 degrees, officials said.

“This hasn’t been experienced in quite some time, and it’s rare,” John Crater, Cal Fire Riverside County division chief, said in a news conference early Friday. “So we’re kind of in uncharted territory with this.”

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It is unclear what caused the leak. Officials conceded at the news conference that they had a lack of familiarity with how to deal with the substance. 

Crater said he had been on the phone all night with experts in other states, who told him the leak could resolve itself in two or three days.